A comprehensive review for machine learning based human papillomavirus detection in forensic identification with multiple medical samples.

Human papillomavirus (HPV) is a sexually transmitted virus. Cervical cancer is one of the highest incidences of cancer, almost all patients are accompanied by HPV infection. In addition, the occurrence of a variety of cancers is also associated with HPV infection. HPV vaccination has gained widespread popularity in recent years with the increase in public health awareness. In this context, HPV testing not only needs to be sensitive and specific but also needs to trace the source of HPV infection. Through machine learning and deep learning, information from medical examinations can be used more effectively. In this review, we discuss recent advances in HPV testing in combination with machine learning and deep learning.

Prediction Model of Residual Neural Network for Pathological Confirmed Lymph Node Metastasis of Ovarian Cancer.

Purpose: We want to develop a model for predicting lymph node status based on positron emission computed tomography (PET) images of untreated ovarian cancer patients. We use the feature map formed by wavelet transform and the parameters obtained by image segmentation to build the model. The model is expected to help clinicians and provide additional information about what to do with first-visit patients. Materials and Methods: Our study included 224 patients with ovarian cancer. We have chosen two main methods to extract information from images. On the one hand, we segmented the image to extract the parameters to evaluate the clustering effect. On the other hand, we used wavelet transform to extract the image's texture information to form the image's feature map. Based on the above two kinds of information, we used residual neural network and support vector machine for modeling. Results: We established a model to predict lymph node metastasis in patients with primary ovarian cancer using PET images. On the training set, our accuracy was 0.8854, AUC: 0.9472, CI: 0.9098-0.9752, sensitivity was 0.9865, and specificity was 0.7952. On the test set, our accuracy was 0.9104, AUC: 0.9259, CI: 0.8417-0.9889, sensitivity was 0.8125, and specificity was 1.0000. Conclusions: We used wavelet transform to process the preoperative medical images of ovarian cancer patients, and the residual neural network can effectively predict the lymph node metastasis of ovarian cancer patients, which is undoubted of great significance for patients' staging and treatment options.